Synopsis
Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.
Cast

Jake Gyllenhaal
Jamie Randall

Anne Hathaway
Maggie Murdock

Oliver Platt
Bruce Winston

Hank Azaria
Dr. Stan Knight

Josh Gad
Josh Randall

Gabriel Macht
Trey Hannigan

Judy Greer
Cindy

Jill Clayburgh
Nancy Randall

George Segal
Dr. James Randall

Kate Jennings Grant
Gina

Katheryn Winnick
"Lisa"

Kimberly Scott
Gail

Peter Friedman
California Man

Nikki DeLoach
Christy

Natalie Gold
Dr. Helen Randall

Megan Ferguson
Farrah

Michael Benjamin Washington
Richard

Bingo O'Malley
Sam

Dorothy Silver
Sophie
Lucy Roucis
UN Convention Parkinson's Speaker
Joan Augustin
Joan

Michael Chernus
Jerry

Kate Easton
Amber

Michael Buffer
Pfizer Convention MC
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