Steve Carell

Gru (voice)

Pierre Coffin

Kevin / Stuart / Bob / Minions (voice)

Alan Arkin

Wild Knuckles (voice)

Taraji P. Henson

Belle Bottom (voice)

Julie Andrews

Gru's Mom (voice)

Jean-Claude Van Damme

Jean Clawed (voice)

Lucy Lawless

Nun-Chuck (voice)

Michelle Yeoh

Master Chow (voice)

Dolph Lundgren

Svengeance (voice)

Danny Trejo

Stronghold (voice)

Russell Brand

Dr. Nefario (voice)

Jimmy O. Yang

Henchman 1 (voice)

Kevin Michael Richardson

Henchman 2 (voice)

John DiMaggio

Henchman 3 (voice)

RZA

Biker (voice)

Michael Beattie

VNC Announcer / Guru Rick (voice)

Will Arnett

Mr. Perkins (voice)

Steve Coogan

Silas Ramsbottom (voice)

Colette Whitaker

Gru's Teacher (voice)

Raymond S. Persi

Birthday Kid (voice)

Kyle Balda

Additional Voices (voice)

Bob Bergen

Additional Voices (voice)

Beau Billingslea

Additional Voices (voice)

Cathy Cavadini

Additional Voices (voice)